Ion Channel Modulation by Photocaged Dioctanoyl PIP2

نویسندگان

  • Junghoon Ha
  • DIOMEDES E. LOGOTHETIS
  • Diomedes Logothetis
  • Matthew Hartman
  • Anthony Spano
  • Frank Chen
  • Rahul Mahajan
  • Vasileios Petrou
  • Ching-Kang Chen
چکیده

ION CHANNEL MODULATION BY PHOTOCAGED DIOCTANOYL PIP2 by Junghoon Ha, BSc. A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science at Virginia Commonwealth University. Virginia Commonwealth University, 2009 Thesis Director: Diomedes E. Logothetis, Ph.D. Chair, Department of Physiology and Biophysics Phosphatidylinositol bisphosphate (PIP2) directly regulates electrophysiological activity in a diverse family of ion channels whether the effect is stimulatory or inhibitory. Much has been unveiled about the apparent affinity and modulatory function of PIP2 using a chemically

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تاریخ انتشار 2016